Health Library

Osmolality urine - series

Indication

An osmolality test measures the concentration of particles in a solution. In this case, the solution is urine.

Procedure

How the test is performed: You are instructed to collect a "clean-catch" (midstream) urine sample. To obtain a clean-catch sample, men or boys should wipe clean the head of the penis. Women or girls need to wash the area between the lips of the vagina with soapy water and rinse well. As you start to urinate, allow a small amount of urine to fall into the toilet bowl (this clears the urethra of contaminants). Then, in a clean container, catch about 1 to 2 ounces of urine and remove the container from the urine stream. Give the container to the health-care provider or assistant.

To collect a urine sample from an infant: Thoroughly wash the area around the urethra. Open a urine-collection bag (a plastic bag with adhesive paper on one end), and place it on your infant. For males, the entire penis can be placed in the bag with the adhesive attached to the skin. For females, the bag is placed over the labia. Place a diaper over the infant (bag and all). Check your baby frequently and remove the bag after the infant has urinated into it. The urine is then drained into a container for transport back to the provider. No special preparation is necessary for this test.

Results

Greater-than-normal measurements may indicate:

• Addison's disease (rare)
• Congestive heart failure
• Shock
• Syndrome of inappropriate ADH secretion

Lower-than-normal measurements may indicate:

• Aldosteronism (very rare)
• Diabetes insipidus (rare)
• Excess fluid intake
• Renal tubular necrosis
• Severe pyelonephritis

Review Date: 7/1/2025  

Reviewed By: Frank D. Brodkey, MD, FCCM, Associate Professor, Section of Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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