Methylnaltrexone bromide (By mouth)
Methylnaltrexone Bromide (meth-il-nal-TREX-one BROE-mide)
Treats constipation caused by narcotic pain medicines.
RelistorThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to methylnaltrexone, or if you have a stomach or bowel blockage.
How to Use This Medicine:
- Your doctor will tell you how much medicine to use. Do not use more than directed.
- Take this medicine with water on an empty stomach at least 30 minutes before the first meal of the day.
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Stop taking other laxatives before you start treatment with this medicine.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or stomach or bowel problems (such as Crohn disease, Ogilvie syndrome, diverticulitis, or cancer).
- This medicine may cause a tear in your stomach or bowels.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chills, increased sweating, anxiety, irritability, yawning
- Severe diarrhea
- Severe stomach pain
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 7/4/2018