Bendamustine (By injection)
Treats chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).
Belrapzo, Bendeka, TreandaThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. You should not receive it if you had an allergic reaction to bendamustine, polyethylene glycol 400, propylene glycol, or monothioglycerol, or if you are pregnant.
How to Use This Medicine:
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
- You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some medicines can affect how bendamustine works. Tell your doctor if you are using ciprofloxacin, fluvoxamine, or omeprazole.
- Do not smoke while you are using this medicine.
Warnings While Using This Medicine:
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Women should continue to use birth control for 6 months and for men 3 months after treatment ends.
- Tell your doctor if you have kidney disease, liver disease, cancer, or any kind of infection.
- Do not breastfeed during treatment and for at least 1 week after the last dose.
- Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
- This medicine may cause the following problems:
- Tumor lysis syndrome (electrolyte and metabolic problems that can be life-threatening)
- Serious skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS)
- Liver problems
- This medicine may make you feel weak or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Change in how much or how often you urinate, lower back or side pain
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Fever, chills, cough, sore throat, body aches
- Pain, redness, swelling, or a lump under your skin where the needle is placed
- Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
- Diarrhea, constipation
- Tiredness, headache
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/10/2021