Chlorthalidone (By mouth)
Treats high blood pressure and fluid retention (edema). This medicine is a diuretic (water pill).
Brand Name(s):There may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to chlorthalidone, sulfa drugs, or to similar medicines.
How to Use This Medicine:
- Your doctor will tell you how much medicine to use. Do not use more than directed.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some foods and medicines can affect how chlorthalidone works. Tell your doctor if you are also using any of the following:
- Bepridil, cholestyramine, colestipol, digoxin, lithium, or tubocurarine
- Low-salt milk
- Other blood pressure medicines
- Steroid medicine
- Do not drink alcohol while you are using this medicine.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart failure, diabetes, gout, lupus, pancreas problems, or trouble urinating. Tell your doctor if you are on a low-salt diet.
- This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blood in the urine or stools, lower back or side pain, trouble urinating
- Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in the hands, feet, or lips
- Dry mouth, increased thirst, muscle cramps, nausea or vomiting
- Fever chills, cough, hoarseness
- Lightheadedness, dizziness, fainting
If you notice these less serious side effects, talk with your doctor:
- Loss of appetite
- Mild diarrhea or stomach upset
- Problems having sex
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/10/2021