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Intraductal papilloma
     
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Intraductal papilloma

 

Intraductal papilloma is a small, noncancerous (benign) tumor that grows in a milk duct of the breast.

Intraductal papilloma occurs most often in women ages 35 to 55. The causes and risk factors are unknown.

Symptoms

 

Symptoms include:

  • Breast lump
  • Nipple discharge, which may be clear or bloodstained

These findings may be in just one breast or in both breasts.

For the most part, these papillomas do not cause pain.

 

Exams and Tests

 

The health care provider might feel a small lump under the nipple, but this lump cannot always be felt. There may be discharge from the nipple. Sometimes, an intraductal papilloma is found on a mammogram or ultrasound, and then diagnosed by a needle biopsy.

If there is a mass or nipple discharge, both mammogram and ultrasound should be performed.

If a woman has nipple discharge, and no abnormal finding on mammogram or ultrasound, then breast MRI is sometimes recommended.

A breast biopsy may be done to rule out cancer. If you have nipple discharge, a surgical biopsy is performed. If you have a lump, sometimes a needle biopsy can be done to make a diagnosis.

 

Treatment

 

The duct is removed with surgery if mammogram, ultrasound, and MRI don't show a lump that can be checked with a needle biopsy. The cells are checked for cancer (biopsy).

 

Outlook (Prognosis)

 

For the most part, intraductal papillomas do not appear to increase the risk of developing breast cancer.

The outcome is excellent for people with one papilloma. The risk for cancer may be higher for:

  • Women with many papillomas
  • Women who get them at an early age
  • Women with a family history of cancer
  • Women who have abnormal cells in the biopsy

 

Possible Complications

 

Complications of surgery can include bleeding, infection, and anesthesia risks. If the biopsy shows cancer, you may need further surgery.

 

When to Contact a Medical Professional

 

Call your provider if you notice any breast discharge or a breast lump.

 

Prevention

 

There is no known way to prevent intraductal papilloma. Breast self-exams and screening mammograms can help detect the disease early.

 

 

References

Davidson NE. Breast cancer and benign breast disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 188.

Hunt KK, Mittlendorf EA. Diseases of the breast. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 20th ed. Philadelphia, PA: Elsevier; 2017:chap 34.

Sasaki J, Geletzke, Kass RB, Klimberg VS, et al. Etiology and management of benign breast disease. In: Bland KI, Copeland EM, Klimberg VS, Gradishar WJ, eds. The Breast: Comprehensive Management of Benign and Malignant Disorders. 5th ed. Philadelphia, PA: Elsevier; 2018:chap 5.

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  • Intraductal papilloma

    Intraductal papilloma

    illustration

  • Abnormal discharge from the nipple

    Abnormal discharge from the nipple

    illustration

  • Core needle biopsy of the breast

    Core needle biopsy of the breast

    illustration

    • Intraductal papilloma

      Intraductal papilloma

      illustration

    • Abnormal discharge from the nipple

      Abnormal discharge from the nipple

      illustration

    • Core needle biopsy of the breast

      Core needle biopsy of the breast

      illustration

    Self Care

     

      Tests for Intraductal papilloma

       
         

        Review Date: 9/15/2019

        Reviewed By: Debra G. Wechter, MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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