Edoxaban (By mouth)
Prevents and treats blood clots, and lowers risk of stroke. This medicine is a blood thinner.
SavaysaThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to edoxaban, or if you have active bleeding.
How to Use This Medicine:
- Your doctor will tell you how much medicine to use. Do not use more than directed.
- If you have trouble swallowing the tablet whole, you may crush and mix it with 2 to 3 ounces of water and give it by mouth or through a gastric tube. The crushed tablets may also be mixed with soft foods (including applesauce).
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
- Some medicines can affect how edoxaban works. Tell your doctor if you are using any of the following:
- Another blood thinner (including clopidogrel, heparin, prasugrel, warfarin)
- NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
- Medicine to treat depression (including citalopram, desvenlafaxine, duloxetine, escitalopram, fluoxetine, paroxetine, sertraline, venlafaxine)
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bleeding problems, spine problems, or a history of back surgery, heart valve disease, or an artificial heart valve.
- This medicine may cause the following problems:
- Increased risk for bleeding
- Increased risk for blood clots in your spine or back after a spinal procedure
- Do not suddenly stop using this medicine without asking your doctor first. You risk of stroke is higher if you stop using this medicine suddenly.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Back pain, numbness, tingling, or muscle weakness in your legs or feet, loss of bladder or bowel control
- Bleeding from your gums or nose, heavy menstrual bleeding
- Bleeding that does not stop, bruising, or weakness
- Coughing up blood, vomiting blood or material that looks like coffee grounds
- Pink or red urine, red or black stools
- Sudden or severe headache, confusion, nausea
If you notice other side effects that you think are caused by this medicine, tell your doctor
Last Updated: 1/4/2018